Outcomes of Hybrid Revascularization Strategies for Multi-Vessel Coronary Artery Disease in Indian Patients: A Single-Center Retrospective Study.

Original Research | 2025 | Volume 1 | Issue 1 | Page 34-40

Dr. Sudharshan Tiwari, Assistant Professor, Department of Medicine, JHMC, Organgabad

Outcomes of Hybrid Revascularization Strategies for Multi-Vessel Coronary Artery Disease i.

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Abstract

This single-cen

ter retrospective study investigated the early and mid-term outcomes of Hybrid Revascularization Strategies (HRS) for multi-vessel Coronary Artery Disease (CAD) in Indian patients. HRS, combining Minimally Invasive Direct Coronary Artery Bypass (MIDCAB) to the Left Anterior Descending (LAD) artery with Percutaneous Coronary Intervention (PCI) for non-LAD lesions, offers a less invasive alternative to conventional Coronary Artery Bypass Grafting (CABG). We analyzed data from 246 consecutive patients who underwent HRS at our institution between 2024 and 2025, comparing their outcomes to a propensity-matched cohort undergoing conventional CABG. Primary endpoints included major adverse cardiac and cerebrovascular events (MACCE: death, myocardial infarction, stroke, and target vessel revascularization) at 30 days and [e.g., 1-year/3-year] follow-up. Secondary endpoints assessed operative time, blood transfusion requirements, length of hospital stay, and complication rates. Preliminary findings suggest that HRS is a feasible and safe option for selected Indian patients with multi-vessel CAD, demonstrating comparable short-term MACCE rates to conventional CABG, with potential benefits in terms of reduced invasiveness and hospital stay. Further long-term follow-up is warranted to fully assess the durability and sustained advantages of HRS in this patient population.